一种地塞米松、长春花碱、环磷酰胺、依托泊苷、甲氨蝶呤和博来霉素（D-VICEMB）方案作为70岁及以上中/高度非霍奇金淋巴瘤患者的一线治疗方案。
A dexamethasone, vinblastine, cyclophosphamide, etoposide, methotrexate and bleomycin (D-VICEMB) protocol as first-line treatment of patients aged 70 years or older affected by intermediate/high grade non-Hodgkin's lymphoma.
作者信息
Angrilli Francesco, Pennese Elsa, Di Marzio Alessandro, Liberatore Elisabetta, Di Lorenzo Roberto, Fioritoni Giuseppe
出版信息
Haematologica. 2002 Nov;87(11):1227-9.
PMID:12414356
Abstract
We treated 30 consecutive untreated patients aged > 70 years with advanced aggressive non-Hodgkin's lymphoma with 6 courses of cyclophosphamide, mitoxantrone, etoposide, bleomycin, vinblastine and dexamethasone (D-VICEMB). The global response was 93%. The 6-year overall survival and progression-free survival were 50%, and disease-free survival was 63%.
摘要
我们采用环磷酰胺、米托蒽醌、依托泊苷、博来霉素、长春碱和地塞米松（D-VICEMB）方案，对30例年龄大于70岁、未经治疗的晚期侵袭性非霍奇金淋巴瘤患者进行了6个疗程的治疗。总体缓解率为93%。6年总生存率和无进展生存率均为50%，无病生存率为63%。
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