Kayhan Fatma Tülin, Ergez Ebru, Hatipoğlu Ayşe, Meriç Ayşenur, Gedikli Orhan, Yiğit Ozgül, Babalioğlu Mustafa, Sezgin Betül
Department of Otolaryngology, 29 Mayis Hospital, 34250 Istanbul, Turkey.
Kulak Burun Bogaz Ihtis Derg. 2002 May-Jun;9(3):184-7.
Many factors have been implicated in the etiopathogenesis of otitis media with effusion (OME). In this study, we investigated the role of allergy and the incidence of allergic rhinitis in patients with OME.
The study included 22 children (17 boys, 5 girls; mean age 7.8 years; range 2 to 12 years) with OME confirmed by findings of physical examination and tympanometry. Patients with high IgE levels and symptoms of allergic rhinitis were further investigated by skin prick tests and nasal smears. The results were compared with those of an age- and sex-matched control group (13 boys, 8 girls; mean age 7.8 years) with no symptoms of otolaryngological diseases.
Symptoms of rhinitis, serum IgE levels, prick test and nasal smear findings suggested a diagnosis of allergic rhinitis in five children with OME (23%), and in one child (4.8%) in the control group. However, this difference did not reach significance (p>0.05).
Identification and appropriate treatment of allergic rhinitis in patients with OME may increase the success rate of OME treatment.
诸多因素与分泌性中耳炎(OME)的发病机制有关。在本研究中,我们调查了过敏因素及OME患者中变应性鼻炎的发病率。
本研究纳入了22例经体格检查和鼓室导抗图检查确诊为OME的儿童(17例男孩,5例女孩;平均年龄7.8岁;范围2至12岁)。对IgE水平高且有变应性鼻炎症状的患者进一步行皮肤点刺试验和鼻涂片检查。将结果与年龄和性别匹配的无耳鼻喉科疾病症状的对照组(13例男孩,8例女孩;平均年龄7.8岁)进行比较。
鼻炎症状、血清IgE水平、点刺试验及鼻涂片检查结果提示,5例OME患儿(23%)及1例对照组患儿(4.8%)诊断为变应性鼻炎。然而,这种差异无统计学意义(p>0.05)。
识别并适当治疗OME患者的变应性鼻炎可能会提高OME的治疗成功率。