Slack Jonathan M W
Developmental Biology Programme, Department of Biology and Biochemistry, University of Bath, Bath BA2 7AY, UK.
Nat Rev Genet. 2002 Nov;3(11):889-95. doi: 10.1038/nrg933.
Conrad Hal Waddington was a leading embryologist and geneticist from the 1930s to the 1950s. He is remembered mainly for his concepts of the 'epigenetic landscape' and 'genetic assimilation'. This article reviews his life and work, and enquires to what extent his ideas are relevant tools for understanding the biological problems of today.
康拉德·哈尔·沃丁顿是20世纪30年代至50年代的一位杰出胚胎学家和遗传学家。他主要因“表观遗传景观”和“遗传同化”的概念而被人们铭记。本文回顾了他的生平与工作,并探讨他的思想在何种程度上是理解当今生物学问题的相关工具。