Scattoni Vincenzo, Roscigno Marco, Raber Marco, Montorsi Francesco, Bertini Roberto, Bua Lina, Da Pozzo Luigi, Rigatti Patrizio
Dipartimento di Urologia, Istituto Scientifico Ospedale San Raffaele, Milano, Italy.
Arch Ital Urol Androl. 2002 Sep;74(3):129-31.
The authors report their experience on the use of a high number of biopsies for the diagnosis of a vesicourethral anastomosis tumor recurrence in patients who underwent radical prostatectomy with a PSA elevation.
Sixty-five patients with PSA > or = 0.4 ng/ml after radical prostatectomy received 6 to 8 transrectal ultrasound (TRUS) guided biopsies of the vesicourethral anastomosis.
The biopsy scheme with 6 random anastomotic biopsies plus additional biopsies through TRUS detectable lesions was able to diagnose a local recurrence in more than 60% of the cases. In presence of a post-operative PSA < 1.0 ng/ml and in absence of ultrasound detectable or palpable lesions a local neoplastic recurrence was detected in 58% of the cases. In presence of a palpable or ultrasound visible lesions, the detection rate increases to 80% of the cases.
作者报告了他们在对前列腺癌根治术后出现PSA升高的患者进行大量活检以诊断膀胱尿道吻合口肿瘤复发方面的经验。
65例前列腺癌根治术后PSA≥0.4 ng/ml的患者接受了6至8次经直肠超声（TRUS）引导下的膀胱尿道吻合口活检。
6次随机吻合口活检加上通过TRUS可检测到的病变进行额外活检的方案能够在超过60%的病例中诊断出局部复发。在术后PSA<1.0 ng/ml且没有超声可检测到的或可触及的病变的情况下，58%的病例检测到局部肿瘤复发。在存在可触及的或超声可见的病变时，检测率提高到80%的病例。
