Gel'tser B I, Frisman M V
Klin Med (Mosk). 2002;80(9):4-9.
The analysis of the literature data on quality of life (QL) in arterial hypertension (AH) demonstrates that ACE inhibitors and calcium antagonists improve QL while such data on diuretics effect are contradictable. The comparison of pharmacological and surgical treatment effects on QL in patients with coronary heart disease shows that functionally and emotionally CHD patients benefit more from coronary artery bypass surgery. In early chronic cardiac failure QL falls because of the necessity to take treatment, lower everyday activity, work limitations. Later, QL deterioration depends on severity of cardiac activity decompensation is independent of central hemodynamics, myocardial contractility and psychological status of the patient. Adequate use of QL assessment may raise efficacy of treatment of circulatory diseases.
对动脉高血压(AH)患者生活质量(QL)的文献数据分析表明,血管紧张素转换酶抑制剂和钙拮抗剂可改善生活质量,而关于利尿剂作用的此类数据则相互矛盾。对冠心病患者生活质量的药物治疗和手术治疗效果比较表明,在功能和情感方面,冠心病患者从冠状动脉搭桥手术中获益更多。在早期慢性心力衰竭中,由于需要接受治疗、日常活动减少、工作受限,生活质量会下降。后来,生活质量的恶化取决于心脏活动失代偿的严重程度,与患者的中心血流动力学、心肌收缩力和心理状态无关。充分利用生活质量评估可能会提高循环系统疾病的治疗效果。