Kober H J, Herbst R
Z Mikrosk Anat Forsch. 1975;89(4):702-17.
The surface architecture of rat esophagus during the ontogeny is studied. Single cilia on the cells of the apical surface can be observed with the scanning electron microscope till the day 17 of the fetal period. Ciliogenesis and function of the single cilia are discussed by literature. Based upon results of our investigations we give the following interpretation: The single cilia are responsible for differentiation of the transitional columnar epithelium. The stop of mitosis, which is connected to constitution of single cilia, allows the formation of cell organelles. About the day 21 after conception ciliary cells are found. Their function is still unknown. They are observed on the esophageal surface at the same time, when primary ciliary cells arise on the trachea of the rat. The columnar epithelial cells transform into a squamous epithelium within 48 hours. The keratinisation and exfoliation of the surface cells occur definitely post-partum.
研究了大鼠食管个体发育过程中的表面结构。在胎儿期第17天之前，用扫描电子显微镜可观察到顶端表面细胞上的单个纤毛。文献中讨论了单个纤毛的纤毛发生和功能。根据我们的研究结果，我们给出以下解释：单个纤毛负责过渡柱状上皮的分化。与单个纤毛形成相关的有丝分裂停止，允许细胞器的形成。在受孕后约21天发现纤毛细胞。它们的功能仍然未知。在大鼠气管上出现初级纤毛细胞的同时，在食管表面也观察到了它们。柱状上皮细胞在48小时内转变为鳞状上皮。表面细胞的角化和脱落肯定发生在产后。
