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[表现为结核性狼疮的肺结核]

[Pulmonary tuberculosis presenting as tubercular lupus].

作者信息

Fays S, Martin S, Barbaud A, Schmutz J L

机构信息

Service de Dermatologie, Hôpital Fournier, Nancy.

出版信息

Rev Mal Respir. 2002 Sep;19(4):519-21.

Abstract

Pulmonary tuberculosis can be associated with skin manifestations. We report a case in which cutaneous tuberculous lesions were associated with asymptomatic pulmonary tuberculosis. A 15-year old woman had four cutaneous tumoral lesions on her face back, a few of which had evolved over a period of several years. They were asymptomatic nodular lesions, with rounded bumps, with, in places, cheloidal features. The biopsy specimen revealed non-caseating epithelioid granulomas with giant cells and the culture grew Mycobacterium tuberculosis. Cavitating pulmonary tuberculosis was then revealed by CT scan and acid-fast bacilli were isolated in her sputum. The skin lesions disappeared with anti-tuberculosis therapy. Cutaneous manifestations of tuberculosis are rare, polymorphous, and can be associated with an underlying visceral infection. Lupus vulgaris is the most common cutaneous manifestation of tuberculosis in industrialised countries, but nevertheless it remains rare and it is a very unusual presenting feature of underlying pulmonary tuberculosis.

摘要

肺结核可伴有皮肤表现。我们报告一例皮肤结核病变与无症状肺结核相关的病例。一名15岁女性面部、背部有4个皮肤肿瘤性病变,其中一些病变已发展数年。它们是无症状的结节性病变,有圆形隆起,部分具有瘢痕疙瘩样特征。活检标本显示有非干酪样上皮样肉芽肿及巨细胞,培养物培养出结核分枝杆菌。随后CT扫描显示有空洞性肺结核,痰中分离出抗酸杆菌。抗结核治疗后皮肤病变消失。结核病的皮肤表现罕见、多样,可与潜在的内脏感染相关。寻常狼疮是工业化国家结核病最常见的皮肤表现,但仍然罕见,且是潜在肺结核非常不寻常的表现特征。

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