Sentinelli S, Covello R, Benevolo M, Licci S, Perrone Donnorso R
U.O. Anatomia Patologica e Citodiagnostica, Polo Oncologico Regina Elena, Via Elio Chianesi 53, I-00144 Roma, Italia.
Pathologica. 2002 Oct;94(5):253-6. doi: 10.1007/s102420200041.
We report the case of a 48-year-old woman with multiple benign metastasizing leiomyomas in both lungs and a single retroperitoneal leiomyoma. The patient underwent surgical resection of the lesions 15 years after total hysterectomy for uterine myomas. Immunohistochemical studies performed on the retroperitoneal and pulmonary neoplasms showed them to be of mesenchymal derivation with smooth muscle differentiation; the samples were negative for HMB-45. Some histogenetic hypotheses for the multiple leiomyomas are presented.
我们报告了一例48岁女性病例，其双肺有多个良性转移性平滑肌瘤以及一个腹膜后平滑肌瘤。该患者因子宫肌瘤行全子宫切除术后15年接受了病变的手术切除。对腹膜后和肺部肿瘤进行的免疫组织化学研究显示，它们来源于间充质，具有平滑肌分化；样本HMB-45检测为阴性。本文提出了关于多发性平滑肌瘤的一些组织发生学假说。
