Kimura Sumiko, Schaumann Blanka A, Shiota Kohei
Department of Anatomy and Developmental Biology, Faculty of Medicine, Kyoto University, Kyoto 606-8501, Japan.
Anat Sci Int. 2002 Mar;77(1):34-46. doi: 10.1046/j.0022-7722.2002.00002.x.
The morphological features of the palmar, plantar and digital areas of the rat were studied and compared to the corresponding human traits. The location and the timing of appearance of the volar pads and flexion creases of human and rat fetuses were investigated to determine the feasibility of using rats as an experimental model for studying the factors influencing early development of the dermatoglyphics in humans. Comparisons between analogous developmental stages of human and rat fetuses demonstrate striking similarities in overall fetal development. However, marked differences between human and rat fetuses were found in the timing of developmental milestones and in some morphological features. Provided that these differences are taken into consideration, rats can serve as a useful experimental model in studies of the utility of the epidermal ridge configurations and flexion creases in medical disorders.
研究了大鼠手掌、足底和指部区域的形态特征,并与相应的人类特征进行了比较。研究了人类和大鼠胎儿掌垫和屈褶的位置及出现时间,以确定将大鼠用作研究影响人类皮纹早期发育因素的实验模型的可行性。人类和大鼠胎儿相似发育阶段的比较表明,整体胎儿发育存在显著相似性。然而,在发育里程碑的时间和一些形态特征方面,人类和大鼠胎儿存在明显差异。只要考虑到这些差异,大鼠可作为研究表皮嵴形态和屈褶在医学疾病中的作用的有用实验模型。