Weiss Avraham, Grossman Ehud, Beloosesky Yichayaou, Grinblat Joseph
Department, Rabin Medical Center, Golda Campus, Sackler School of Medicine, Tel-Aviv University, Tel Aviv, Israel.
Arch Intern Med. 2002 Nov 11;162(20):2369-74. doi: 10.1001/archinte.162.20.2369.
Orthostatic hypotension (OH) is a common finding among older patients. We designed a study to examine the prevalence and consistency of OH during the day.
A total of 502 inpatients (241 men and 261 women) with a mean age of 81.6 years were included in the study. Orthostatic tests were performed 3 times during the day, 30 minutes after meals. In 13 patients only 2 sets of measurements were obtained, and they were omitted from some of the calculations. Orthostatic hypotension was defined as a fall of at least 20 mm Hg in systolic blood pressure and/or 10 mm Hg in diastolic blood pressure on assuming an upright posture.
Three hundred thirty-two (67.9%) of 489 patients experienced OH at least once during the day. Of these, 170 patients (34.8% of the 489) had OH at least twice (persistent OH) and 162 patients (33.1%) experienced OH only once (variable OH). Diastolic OH was more prevalent than systolic OH (57.3% vs 43.4%; P<.001). The intraindividual consistency of OH was low (kappa = 0.2). Orthostatic hypotension was observed less frequently during the evening than during the morning and afternoon (P<.05 vs morning and P =.003 vs afternoon). The difference between meals' constituents (light vs heavy meals) did not affect the prevalence of OH.
Orthostatic hypotension is very common in the elderly, and diastolic OH is more common than systolic OH. The prevalence of OH is the lowest during the evening, and meals do not increase the prevalence of OH. The intraindividual consistency of OH during the day is poor. Thus, in elderly patients, more attention should be paid to diastolic OH and the diagnosis should be based on repeated measurements.
体位性低血压(OH)在老年患者中很常见。我们设计了一项研究来调查白天OH的患病率及一致性。
本研究共纳入502名住院患者(241名男性和261名女性),平均年龄81.6岁。白天在餐后30分钟进行3次体位测试。13名患者仅获得2组测量值,部分计算将其排除。体位性低血压定义为站立后收缩压至少下降20 mmHg和/或舒张压至少下降10 mmHg。
489名患者中有332名(67.9%)在白天至少经历过一次OH。其中,170名患者(占489名的34.8%)至少经历过两次OH(持续性OH),162名患者(33.1%)仅经历过一次OH(波动性OH)。舒张期OH比收缩期OH更常见(57.3%对43.4%;P<0.001)。OH的个体内一致性较低(kappa = 0.2)。与上午和下午相比,晚上观察到体位性低血压的频率较低(与上午相比P<0.05,与下午相比P = 0.003)。餐食成分(清淡与丰盛餐食)之间的差异不影响OH的患病率。
体位性低血压在老年人中非常常见,舒张期OH比收缩期OH更常见。OH的患病率在晚上最低,进餐不会增加OH的患病率。白天OH的个体内一致性较差。因此对于老年患者,应更多关注舒张期OH,且诊断应基于重复测量。