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[声门下癌]

[Subglottic carcinoma].

作者信息

Bahar Gideon, Nageris Ben I, Spitzer Tomas, Popovtzer Aharon, Mharshak Gideon, Feinmesser Refael

机构信息

Department of Otorhinolaryngology, Rabin Medical Center, Beilinson Campus, Petah Tikva, Israel.

出版信息

Harefuah. 2002 Oct;141(10):914-8, 929.

Abstract

Subglottic malignancies are rare. They constitute about 1% of laryngeal cancer. Most of these malignancies are squamous cell carcinoma. In this article were describe various definitions concerning the borders of the subglottic region. A summary of pathophysiology and behavior of cancer in this location is presented. The incidence of primary subglottic carcinoma is low. The origin of most cancers in this area is the glottic cancer that extends into the subglottic region. The tumor tends to spread through lymphatic channels to the paraglottic and preglottic (delphian) nodes and secondary to the jugular chain. The delayed diagnosis is due to the lack of symptoms in the early stage of the disease and the hidden location of the tumor. The presenting symptoms are usually dyspnea and stridor. Direct laryngoscopy is essential for early detection of the tumor and the use of CT and MRI is advocated. Therapy is usually radical. Total laryngectomy and radiation therapy have both been advocated. Between 1995 and 2000, 126 patients with laryngeal squamous cell carcinoma were presented to our department. Our experience in diagnosing and treating subglottic cancer in 4 patients is hereby described. The latest literature on the subject is reviewed.

摘要

声门下恶性肿瘤较为罕见。它们约占喉癌的1%。这些恶性肿瘤大多为鳞状细胞癌。在本文中,我们描述了关于声门下区域边界的各种定义。本文还总结了该部位癌症的病理生理学及特性。原发性声门下癌的发病率较低。该区域的大多数癌症起源于延伸至声门下区域的声门癌。肿瘤往往通过淋巴管道扩散至声门旁和声门前(德尔菲安)淋巴结,继而扩散至颈静脉链。诊断延迟是由于疾病早期缺乏症状以及肿瘤位置隐匿。出现的症状通常为呼吸困难和喘鸣。直接喉镜检查对于早期发现肿瘤至关重要,同时提倡使用CT和MRI。治疗通常较为彻底。全喉切除术和放射治疗均有人主张。1995年至2000年间,有126例喉鳞状细胞癌患者前来我科就诊。在此描述我们对4例声门下癌的诊断和治疗经验。并对该主题的最新文献进行综述。

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