Berger G, Harwood A R, Bryce D P, van Nostrand A W
J Otolaryngol. 1985 Feb;14(1):1-6.
In a clinical and pathological study of patients who had failed radiotherapy for T1 glottic carcinoma, nine patients were encountered who presented with hoarseness, and were considered clinically to have glottic carcinoma at an early stage. Whole organ sections of the laryngectomy specimens showed them to be tumors arising in the subglottic region with involvement of the vocal cord as a late manifestation of their disease. The clinical and pathological features of these nine patients and their tumors are discussed with emphasis on how the diagnosis may be made prior to embarking upon therapy.
在一项针对T1期声门癌放疗失败患者的临床和病理研究中,遇到了9例出现声音嘶哑的患者,临床认为这些患者处于声门癌早期。喉切除术标本的全器官切片显示,这些肿瘤起源于声门下区域,声带受累是疾病的晚期表现。本文讨论了这9例患者及其肿瘤的临床和病理特征,重点在于如何在开始治疗前做出诊断。