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禁食家兔房水中葡萄糖、丙酮酸、L-乳酸和柠檬酸浓度与年龄的关系。

Glucose, pyruvate, L-lactate, and citrate concentrations in the aqueous humour of fasting rabbits in relation to age.

作者信息

Laursen A B, Lorentzen S E

出版信息

Acta Ophthalmol (Copenh). 1975 Sep;53(4):553-62. doi: 10.1111/j.1755-3768.1975.tb01774.x.

DOI:10.1111/j.1755-3768.1975.tb01774.x
PMID:1242277
Abstract

Results are reported of determinations of glucose, pyruvate, l-lactate and citrate concentrations in aqueous humour from 42 fasting albino rabbits aged from 8 months to 9 years. The glucose concentrations decreased significantly with increasing age. The pyruvate and l-lactate concentrations as well as the ratios of l-lactate/pyruvate did not change significantly with age. However, the pyruvate concentrations were higher and the l-lactate/pyruvate ratios were lower in the 2-year-old rabbits than in the others. The citrate concentrations were found to rise with increasing age. Because of wide ranges of variation between individuals of the same age groups, the parameters in question have limited value in the evaluation of the energy metabolism of the anterior eye segment.

摘要

报告了对42只年龄在8个月至9岁之间的禁食白化兔房水中葡萄糖、丙酮酸、L-乳酸和柠檬酸浓度的测定结果。葡萄糖浓度随年龄增长显著降低。丙酮酸和L-乳酸浓度以及L-乳酸/丙酮酸比值并未随年龄显著变化。然而,2岁兔子的丙酮酸浓度较高,L-乳酸/丙酮酸比值低于其他兔子。发现柠檬酸浓度随年龄增长而升高。由于同一年龄组个体间差异范围较大,所讨论的参数在评估眼前节能量代谢方面价值有限。

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