Palmieri I, Angelini D, Mostacci F D, Gallo A, Piro F, Puntillo F
I Clinica Chirurgica, Università degli Studi La Sapienza di Roma.
G Chir. 2002 Jun-Jul;23(6-7):247-9.
The Authors present a case of synchronous double gastric carcinoma in a 75-year-old man. Synchronous multiple gastric carcinoma (SMGC) constitutes 4% to 10% of all gastric cancers. It exhibits several clinicopathological characteristics that differ from those of solitary cancers: SMGC occurs in older people (men more than women); early carcinoma is observed more frequently in SMGC than in solitary cancers; the rate of intestinal type lesions is higher in multiple than in single gastric carcinoma. With regard to the pathogenesis of multiple gastric cancer, the theory proposing a multicentric or independent origin rather than the local or distant spread of one cancer (multifocality) has been favored.
作者报告了一例75岁男性同步性双原发胃癌病例。同步性多原发胃癌（SMGC）占所有胃癌的4%至10%。它具有一些与单发癌不同的临床病理特征：SMGC多见于老年人（男性多于女性）；与单发癌相比，SMGC中早期癌更为常见；多原发胃癌中肠型病变的发生率高于单发性胃癌。关于多原发胃癌的发病机制，多中心或独立起源而非一个癌灶的局部或远处播散（多灶性）的理论更受青睐。
