Bogusz M, Cholewa L, Pach J, Mlodkowska K
Arch Toxicol. 1975 Feb 14;33(2):141-9. doi: 10.1007/BF00353239.
In 47 patients treated at the Toxicological Clinic in Krakow for coal stove-gas poisoning, the aspartate aminotransferase, lactate dehydrogenase, LDH1 isoenzyme activities, and the lactate level were studied. Findings were compared with those of earlier investigations carried out on a group of patients poisoned by lighting gas; qualitatively changes in both groups were similar. The biochemical parameters studied aided in quantitative evaluation of the patients' condition: a threefold increase in lactate level on admission to the hospital and a likewise threefold increase in aspartate aminotransferase activity after 24 hrs of treatment are indications of severe poisoning.
在克拉科夫毒理诊所接受治疗的47例煤炉煤气中毒患者中,对其天冬氨酸转氨酶、乳酸脱氢酶、乳酸脱氢酶1同工酶活性及乳酸水平进行了研究。研究结果与之前对一组照明气中毒患者进行的调查结果进行了比较;两组在定性变化上相似。所研究的生化参数有助于对患者病情进行定量评估:入院时乳酸水平增加三倍,治疗24小时后天冬氨酸转氨酶活性同样增加三倍,均表明中毒严重。