Kelve Merike, Kuusksalu Anne, Lopp Annika, Reintamm Tõnu
Laboratory of Molecular Genetics, National Institute of Chemical Physics and Biophysics, Akadeemia tee 23, 12618, Tallinn, Estonia.
J Biotechnol. 2003 Jan 23;100(2):177-80. doi: 10.1016/s0168-1656(02)00254-7.
A high (2',5')oligoadenylate (2-5A) synthetase activity was found in the marine sponge Geodia cydonium. Here we demonstrate that the 2-5A synthetase activity is present also in other sponge species although the level of the 2-5A synthetase activity varies in several magnitudes in different sponges. The 2-5A synthesizing activity was maintained in the primary culture produced from a sponge.
在海洋海绵地穴海绵（Geodia cydonium）中发现了高活性的（2'，5'）寡腺苷酸（2-5A）合成酶。在此我们证明，2-5A合成酶活性在其他海绵物种中也存在，尽管在不同海绵中2-5A合成酶活性水平在几个数量级上有所不同。2-5A合成活性在海绵产生的原代培养物中得以维持。
