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老年人癫痫:管理问题

Epilepsy in elderly people: management issues.

作者信息

Tallis Ray, Boon Paul, Perucca Emilio, Stephen Linda

机构信息

Department of Gerontology, University of Manchester, UK.

出版信息

Epileptic Disord. 2002 Oct;4 Suppl 2:S33-9.

Abstract

Epilepsy in elderly people is far more common than many doctors realise. The prevalence and incidence are frequently underestimated due to underdiagnosis or misdiagnosis of the condition. As the proportion of older people in the population grows, the management of epilepsy in this population will become increasingly important. Elderly people are especially susceptible to the consequences of seizures, particularly loss of self-confidence, decreased independence, and "falls" resulting in physical injury. Establishing the diagnosis of epilepsy in old age can be more difficult than in younger patients due to the extensive range of differential diagnoses and a far higher prevalence of concomitant disease. Treatment strategies are demanding; they must allow for the complexities of co-morbidity, co-medication, alterations in drug handling, and drug effects on an aging body. Together with a growing array of antiepileptic medication from which to choose, these factors make the management of epilepsy in elderly people particularly challenging.

摘要

老年人癫痫远比许多医生意识到的更为常见。由于该病症的诊断不足或误诊,其患病率和发病率常常被低估。随着老年人口在总人口中的比例不断增加,这一人群的癫痫管理将变得越发重要。老年人尤其容易受到癫痫发作后果的影响,特别是自信心丧失、独立性下降以及导致身体受伤的“跌倒”。由于鉴别诊断范围广泛且合并症的患病率高得多,在老年人中确立癫痫诊断可能比年轻患者更困难。治疗策略要求很高;它们必须考虑到合并症、联合用药、药物处理变化以及药物对衰老身体的影响等复杂性。再加上可供选择的抗癫痫药物种类越来越多,这些因素使得老年人癫痫的管理极具挑战性。

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