[大脑半球切除术患者中N(18)正中神经体感诱发电位的起源研究]
[Origin of N(18) median nerve somatosensory evoked potentials studied in patients with hemispherectomy].
作者信息
Xu Yulun, Liu Shuling, Zhao Jizong, Pan Yingfu
机构信息
Department of Neurosurgery, Tiantan Hospital Affiliated to Capital University of Medical Sciences, Beijing 100050, China.
出版信息
Zhonghua Yi Xue Za Zhi. 2002 Aug 25;82(16):1127-9.
OBJECTIVE
To probe into the neural generators of the median nerve (MN) somatosensory evoked potentials (SEP) in patients after hemispherectomy, especially with regard to N(18).
METHODS
SEP induced by median nerve stimulation with both cephalic and noncephalic references were recorded in 20 patients with hemispherectomy entailing massive retrograde degeneration of thalamocortical, midbrain and pontine neurons documented by MRI evidence. Twelve dga and Aex matclod healty persons were used as controls.
RESULTS
No additional focal response (cortical N(20)) was detected over the hemisphere-ectomized lateral scalp in all patients. The positive P(14) and negative N(18) scalp far-fields were preserved and the latencies of with the 12.5 +/- 0.8 ms and 17.6 +/- 1.6 ms respectively. The preserved N(18) response reflected the neural activity below the pons.
CONCLUSION
The N(18) neural generators are located in the medulla.
目的
探究大脑半球切除术后患者正中神经体感诱发电位（SEP）的神经发生器，尤其是关于N(18)。
方法
对20例大脑半球切除术患者进行记录，通过磁共振成像（MRI）证据证实这些患者存在丘脑皮质、中脑和脑桥神经元的大量逆行性变性，采用头侧和非头侧参考电极记录正中神经刺激诱发的SEP。选取12名年龄和性别匹配的健康人作为对照。
结果
所有患者在大脑半球切除侧头皮上均未检测到额外的局灶性反应（皮质N(20)）。头皮远场正性P(14)和负性N(18)得以保留，潜伏期分别为12.5±0.8毫秒和17.6±1.6毫秒。保留的N(18)反应反映了脑桥以下的神经活动。
结论
N(18)神经发生器位于延髓。
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