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Possibilities of the application of regression analysis and analysis of variance. II. Assessment and comparison of acute toxicity: presentation and practical application of the interactive computer program "LD50-MORTALITY".

作者信息

Arambasić M B, Pitić L J, Jeremić D, Adnadjević D

机构信息

Pharmaceutical Factory GALENIKA a.d., Quality Control Center, Department of Biological Control, Batajnicki put b.b., Beograd-Zemun, Yugoslavia.

出版信息

Boll Chim Farm. 2002 Jul-Aug;141(4):290-8.

PMID:12426817
Abstract

The paper presents the interactive computer program "LD50-MORTALITY", written in the program language BASIC and used for the assessment of the acute toxicity (calculation of LD50 and other LD values) based on the algorithm of the Finney's probit analysis method. The correctness of the program execution has been shown on the test-example of assessment the acute toxicity (LD50 an LD90) of insecticide rotenone on Macrosiphonelia sanborni (the example is taken from the literature on probit analysis presentation). The results obtained by the program execution have been identical or similar to those given in the example. The results of the assessment and comparison of LD50 have also been presented.

摘要

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