丘脑底核脑深部电刺激术对帕金森病患者情绪的影响：24例连续病例系列研究
Effect on mood of subthalamic DBS for Parkinson's disease: a consecutive series of 24 patients.
作者信息
Berney A, Vingerhoets F, Perrin A, Guex P, Villemure J-G, Burkhard P R, Benkelfat C, Ghika J
机构信息
Department of Psychiatry, CHUV, Lausanne, Switzerland.
出版信息
Neurology. 2002 Nov 12;59(9):1427-9. doi: 10.1212/01.wnl.0000032756.14298.18.
A series of 24 consecutive PD patients were prospectively studied prior to and within 6 months postoperatively for mood, motor, and cognitive status to investigate the effects on mood of subthalamic deep brain stimulation (DBS) in PD. In six patients (25%), mood state worsened significantly, and three were transiently suicidal despite clear motor improvement. Caregivers and patients should be educated about the potential impact of this neurosurgical procedure on mood.
对24例连续性帕金森病（PD）患者进行前瞻性研究，在术前及术后6个月内评估其情绪、运动和认知状态，以调查丘脑底核深部脑刺激（DBS）对PD患者情绪的影响。6例患者（25%）情绪状态显著恶化，3例尽管运动明显改善但出现短暂自杀倾向。应让护理人员和患者了解这种神经外科手术对情绪的潜在影响。
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