Clinical and Experimental Neuropsychology Laboratory, University of Geneva, 1205 Geneva, Switzerland.
Neuropsychology Unit, Neurology Department, University Hospitals of Geneva, 1205 Geneva, Switzerland.
Soc Cogn Affect Neurosci. 2020 Jul 1;15(5):599-613. doi: 10.1093/scan/nsaa076.
The basal ganglia (BG) and the cerebellum historically have been relegated to a functional role in producing or modulating motor output. Recent research, however, has emphasized the importance of these subcortical structures in multiple functional domains, including affective processes such as emotion recognition, subjective feeling elicitation and reward valuation. The pathways through the thalamus that connect the BG and cerebellum directly to each other and with extensive regions of the cortex provide a structural basis for their combined influence on limbic function. By regulating cortical oscillations to guide learning and strengthening rewarded behaviors or thought patterns to achieve a desired goal state, these regions can shape the way an individual processes emotional stimuli. This review will discuss the basic structure and function of the BG and cerebellum and propose an updated view of their functional role in human affective processing.
基底神经节（BG）和小脑在历史上一直被认为在产生或调节运动输出方面具有功能作用。然而，最近的研究强调了这些皮质下结构在多个功能领域的重要性，包括情感过程，如情绪识别、主观感受诱发和奖励评估。通过丘脑连接 BG 和小脑的通路，直接连接到彼此以及与皮质的广泛区域，为它们对边缘功能的联合影响提供了结构基础。通过调节皮层振荡来指导学习，并强化奖励行为或思维模式以达到期望的目标状态，这些区域可以塑造个体处理情绪刺激的方式。这篇综述将讨论 BG 和小脑的基本结构和功能，并提出它们在人类情感处理中的功能作用的新观点。
