Ohuchi S, Koizumi J, Kin H, Ohsawa S, Izumoto H, Ishihara K, Kawazoe K
Iwate Medical University Memorial Heart Center, Morioka, Japan.
Kyobu Geka. 2002 Nov;55(12):1011-3.
Osteogenesis imperfecta is a disease in which fragile bones readily cause fracture. Valvular disease concurrently develops. However, the surgery-related mortality rate is approximately 30%. In this study, we report 2 patients with osteogenesis imperfecta who underwent valvular heart surgery. Patient 1 was a 31-year-old male. He had previously been diagnosed as having osteogenesis imperfecta. Echocardiography suggested aortic valve insufficiency, and aortic valve replacement was performed. Patient 2 was a 59-year-old male. During admission, osteogenesis imperfecta was diagnosed. Echocardiography suggested mitral valve insufficiency, and mitral valve plasty was performed. In the 2 patients, intraoperative hemorrhage was marked. However, there were no fatal complications. We also reviewed the literature.
成骨不全是一种骨骼脆弱易引发骨折的疾病。同时会并发瓣膜疾病。然而，手术相关死亡率约为30%。在本研究中，我们报告了2例接受心脏瓣膜手术的成骨不全患者。患者1为31岁男性。他此前被诊断为成骨不全。超声心动图提示主动脉瓣关闭不全，遂行主动脉瓣置换术。患者2为59岁男性。入院期间被诊断为成骨不全。超声心动图提示二尖瓣关闭不全，遂行二尖瓣成形术。这2例患者术中出血明显。然而，未出现致命并发症。我们还查阅了相关文献。
