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硫酸镁对乙酰水杨酸和碳酸锂在人体肠道内吸收的影响。

The effect of magnesium sulfate on the absorption of acetylsalicylic acid and lithium carbonate from the human intestine.

作者信息

Sorensen P N, Lindkaer-Jensen S, Dijk A, Maes R A, Drost R H

出版信息

Arch Toxicol. 1975 Oct 20;34(2):121-7. doi: 10.1007/BF00353312.

DOI:10.1007/BF00353312
PMID:1242885
Abstract

Magnesium sulfate given orally in a hypertonic or isotonic solution did not alter the absorption of therapeutic doses of acetylsalicylic acid or lithium carbonate, despite a purgative effect in 10 volunteers. The concentration of magnesium in serum remained unchanged during the experiments.

摘要

在10名志愿者中，口服高渗或等渗溶液的硫酸镁虽有泻下作用，但并未改变治疗剂量的乙酰水杨酸或碳酸锂的吸收。实验过程中血清镁浓度保持不变。

相似文献

1
The effect of magnesium sulfate on the absorption of acetylsalicylic acid and lithium carbonate from the human intestine.硫酸镁对乙酰水杨酸和碳酸锂在人体肠道内吸收的影响。
Arch Toxicol. 1975 Oct 20;34(2):121-7. doi: 10.1007/BF00353312.
2
[Osmotic laxatives and absorption of drugs from the intestine].[渗透性泻药与药物的肠道吸收]
Ugeskr Laeger. 1975 Jan 20;137(4):192-5.
3
Inhibition of salicylate and lithium absorption in the human intestine by copper sulfate.硫酸铜对人体肠道中水杨酸盐和锂吸收的抑制作用。
Arch Toxicol. 1976 Jun 8;35(3):175-9. doi: 10.1007/BF00293564.
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[Circulatory effects of isotonic and hypotonic solutions. I. The effect of magnesium sulfate on the blood vessels of the lower extremities in human].[等渗和低渗溶液的循环效应。I. 硫酸镁对人体下肢血管的作用]
Naunyn Schmiedebergs Arch Exp Pathol Pharmakol. 1956;227(5):400-8.
5
Inhibition of aspirin absorption by activated charcoal and apomorphine.活性炭和阿扑吗啡对阿司匹林吸收的抑制作用。
Clin Pharmacol Ther. 1969 Sep-Oct;10(5):710-3. doi: 10.1002/cpt1969105710.
6
Effect of antacid on the bioavailabiity of lithium carbonate.抗酸剂对碳酸锂生物利用度的影响。
Clin Pharm. 1984 May-Jun;3(3):284-7.
7
Dissolution rates and serum salicylate levels with acetylsalicylic acid (B.P.) and acetylsalicylic acid in "fine-particle" form.英国药典（B.P.）阿司匹林及“细颗粒”形式阿司匹林的溶出速率和血清水杨酸水平。
J Assoc Physicians India. 1971 Jun;19(6):457-60.
8
[Letter: Copper sulfate and absorption inhibition].[信件：硫酸铜与吸收抑制]
Ugeskr Laeger. 1975 Oct 27;137(44):2583-4.
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Absorption of acetylsalicylic acid b a normal and an atrophic gastic mucosa.乙酰水杨酸在正常和萎缩性胃黏膜中的吸收情况。
Scand J Gastroenterol. 1969;4(3):269-73.
10
[Study of salicylemia after absorption of coated acetylsalicylic acid; comparison with the results obtained with classical preparations].[包衣乙酰水杨酸吸收后水杨酸盐血症的研究；与经典制剂所得结果的比较]
Sem Ther. 1965 Dec;41(10):578-81.

引用本文的文献

1
Gastric emptying. Risk versus benefit in the treatment of acute poisoning.胃排空。急性中毒治疗中的风险与获益
Med Toxicol. 1986 Mar-Apr;1(2):142-53. doi: 10.1007/BF03259833.
2
Cathartics and laxatives. Do they still have a place in management of the poisoned patient?泻药。它们在中毒患者的治疗中仍有一席之地吗？
Med Toxicol. 1986 Jul-Aug;1(4):247-52. doi: 10.1007/BF03259841.

本文引用的文献

1
Transport pathways in biological membranes.生物膜中的运输途径。
Annu Rev Physiol. 1974;36:17-49. doi: 10.1146/annurev.ph.36.030174.000313.
2
The osmotic effects of some simple molecules and ions on gastric emptying.一些简单分子和离子对胃排空的渗透作用。
J Physiol. 1960 Dec;154(2):254-69. doi: 10.1113/jphysiol.1960.sp006577.
3
EFFECTS OF CHOLINERGIC AGENTS ON INTESTINAL ABSORPTION OF MAGNESIUM BY RABBITS.胆碱能药物对家兔肠道镁吸收的影响
Acta Pharmacol Toxicol (Copenh). 1963;20:97-108. doi: 10.1111/j.1600-0773.1963.tb01724.x.
4
A simple fluorometric procedure for determining salicylic acid in biologic tissues.一种用于测定生物组织中水杨酸的简单荧光测定法。
J Lab Clin Med. 1959 Nov;54:769-72.
5
Biopharmaceutics: absorption aspects.生物药剂学：吸收方面
J Pharm Sci. 1961 May;50:359-87. doi: 10.1002/jps.2600500502.
6
Trends in the therapy of acute poisonings.急性中毒的治疗趋势
Clin Pharmacol Ther. 1966 May-Jun;7(3):279-99. doi: 10.1002/cpt196673279.
7
Physiological transport of drugs.药物的生理转运
Adv Drug Res. 1964;1:71-106.
8
Effect of sodium sulphate and castor oil on drug absorption from the human intestine.硫酸钠和蓖麻油对药物从人体肠道吸收的影响。
Ann Clin Res. 1974 Feb;6(1):19-24.
9
[Clinical course and therapy of a successfully treated severe bromisovalerinylcarbamide, methaqualone, and meprobamate poisoning in a 12-year-old child].[一名12岁儿童成功治疗重度溴米索伐、甲喹酮和眠尔通中毒的临床过程及治疗]
Arch Toxikol. 1973;30(2):95-102.
10
[Pheniramine(Avil) poisoning in a young child].[一名幼儿的非尼拉敏（阿维）中毒]
Arch Toxikol. 1972;29(4):317-24.