成年大鼠在行为学剂量的 Δ⁹-四氢大麻酚长期治疗后的骨髓增生
Myeloid hyperplasia in growing rats after chronic treatment with delta 9-THC at behavioral doses.
作者信息
Giusti G V, Carnevale A
出版信息
Arch Toxicol. 1975 Oct 20;34(2):169-72. doi: 10.1007/BF00353318.
PMID:1242890
Abstract
Delta 9-THC at the dose of 1 mg/kg/die was administered subcutaneously in growing rats, from the second to the 30th day of life. A statistically significant myeloid hyperplasia was demonstrated, which persisted up to 4 months after the end of the treatment, together with significant blood granulocytosis.
摘要
在新生大鼠出生后第2天至第30天，以1毫克/千克/天的剂量皮下注射δ-9-四氢大麻酚。结果显示出具有统计学意义的髓细胞增生，这种增生在治疗结束后持续长达4个月，同时伴有明显的血液粒细胞增多。
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