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硫烷基化四甘醇:一种用于水溶性单层保护金簇的新型配体。

Thioalkylated tetraethylene glycol: a new ligand for water soluble monolayer protected gold clusters.

作者信息

Kanaras Antonios G, Kamounah Fadhil S, Schaumburg Kjeld, Kiely Christopher J, Brust Mathias

机构信息

Centre for Nanoscale Science, Department of Chemistry, University of Liverpool, Liverpool, UK L69 7ZD.

出版信息

Chem Commun (Camb). 2002 Oct 21(20):2294-5. doi: 10.1039/b207838b.

DOI:10.1039/b207838b
PMID:12430408
Abstract

Ligand-stabilised, water-soluble gold nanoparticles of two different size ranges (2-4 and 5-8 nm) are readily prepared using monohydroxy (1-mercaptoundec-11-yl) tetraethylene glycol as a novel capping agent. These nanoparticles are as stable as alkylthiol-capped monolayer protected clusters (MPCs) and do not aggregate from aqueous solution under a wide range of stringent conditions. It is expected that this new material will be useful for a number of bio-analytical applications.

摘要

使用单羟基(1-巯基十一烷基)四甘醇作为新型封端剂,可以轻松制备出两种不同尺寸范围(2 - 4纳米和5 - 8纳米)的配体稳定的水溶性金纳米颗粒。这些纳米颗粒与烷基硫醇封端的单层保护簇(MPC)一样稳定,并且在广泛的严格条件下不会从水溶液中聚集。预计这种新材料将用于许多生物分析应用。

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