• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

Hammett analysis of a C-C hydrolase-catalysed reaction using synthetic 6-aryl-2-hydroxy-6-ketohexa-2,4-dienoic acid substrates.

作者信息

Speare Damian M, Olf Petra, Bugg Timothy D H

机构信息

Department of Chemistry, University of Warwick, Coventry, UK CV4 7AL.

出版信息

Chem Commun (Camb). 2002 Oct 21(20):2304-5. doi: 10.1039/b208168g.

DOI:10.1039/b208168g
PMID:12430413
Abstract

A Hammett plot (rho = -0.71) has been measured for C-C hydrolase enzyme BphD from Pseudomonas LB400, using six 6-aryl-2-hydroxy-6-ketohexa-2,4-dienoic acids synthesised by a Heck coupling strategy.

摘要

相似文献

1
Hammett analysis of a C-C hydrolase-catalysed reaction using synthetic 6-aryl-2-hydroxy-6-ketohexa-2,4-dienoic acid substrates.
Chem Commun (Camb). 2002 Oct 21(20):2304-5. doi: 10.1039/b208168g.
2
Synthetic 6-aryl-2-hydroxy-6-ketohexa-2,4-dienoic acid substrates for C-C hydrolase BphD: investigation of a general base catalytic mechanism.用于C-C水解酶BphD的合成6-芳基-2-羟基-6-氧代己-2,4-二烯酸底物：一般碱催化机制的研究
Org Biomol Chem. 2004 Oct 21;2(20):2942-50. doi: 10.1039/B410322J. Epub 2004 Sep 16.
3
Stereochemistry of the reaction catalysed by 2-hydroxy-6-keto-6-phenyl-hexa-2,4-dienoic acid 5,6-hydrolase (BphD).
Chem Commun (Camb). 2005 Jan 7(1):130-2. doi: 10.1039/b415491f. Epub 2004 Nov 26.
4
Investigation of a general base mechanism for ester hydrolysis in C-C hydrolase enzymes of the alpha/beta-hydrolase superfamily: a novel mechanism for the serine catalytic triad.α/β-水解酶超家族C-C水解酶中酯水解通用碱机制的研究：丝氨酸催化三联体的新机制
Org Biomol Chem. 2007 Feb 7;5(3):507-13. doi: 10.1039/b615605c. Epub 2006 Dec 19.
5
Regulation of the enzymes of the beta-ketoadipate pathway in Moraxella calcoacetica. 3. Effects of 3-hydroxy-4-methylbenzoate on the synthesis of enzymes of the protocatechuate branch.钙乙酸不动杆菌中β-酮己二酸途径酶的调控。3. 3-羟基-4-甲基苯甲酸对原儿茶酸支路酶合成的影响。
Eur J Biochem. 1968 Jan;3(3):305-11. doi: 10.1111/j.1432-1033.1968.tb19530.x.
6
Comparative specificities of two evolutionarily divergent hydrolases involved in microbial degradation of polychlorinated biphenyls.参与多氯联苯微生物降解的两种进化上不同的水解酶的比较特异性
J Bacteriol. 2001 Mar;183(5):1511-6. doi: 10.1128/JB.183.5.1511-1516.2001.
7
Regulation of the enzymes of the beta-ketoadipate pathway in Moraxella calcoacetica. 2. The role of protocatechuate as inducer.钙乙酸不动杆菌中β-酮己二酸途径酶的调控。2. 原儿茶酸作为诱导剂的作用。
Eur J Biochem. 1968 Jan;3(3):293-304. doi: 10.1111/j.1432-1033.1968.tb19529.x.
8
Regulation of the enzymes of the beta-ketoadipate pathway in Moraxella calcoacetica. 4. Constitutive synthesis of beta-ketoadipate succinyl-CoA transferases II and 3.钙乙酸不动杆菌中β-酮己二酸途径酶的调控。4. β-酮己二酸琥珀酰辅酶A转移酶II和3的组成型合成。
Eur J Biochem. 1968 Jan;3(3):312-7. doi: 10.1111/j.1432-1033.1968.tb19531.x.
9
The regulation of the -ketoadipate pathway in Pseudomonas acidovorans and Pseudomonas testosteroni.食酸假单胞菌和睾丸酮假单胞菌中α-酮己二酸途径的调控
J Gen Microbiol. 1972 Dec;73(3):455-64. doi: 10.1099/00221287-73-3-455.
10
Kinetic and structural insight into the mechanism of BphD, a C-C bond hydrolase from the biphenyl degradation pathway.对来自联苯降解途径的碳-碳键水解酶BphD作用机制的动力学和结构洞察。
Biochemistry. 2006 Sep 19;45(37):11071-86. doi: 10.1021/bi0611098.

引用本文的文献

1
A Hammett Study of Clostridium acetobutylicum Alcohol Dehydrogenase (CaADH): An Enzyme with Remarkable Substrate Promiscuity and Utility for Organic Synthesis.丙酮丁醇梭菌乙醇脱氢酶（CaADH）的哈米特研究：一种具有显著底物选择性和有机合成用途的酶
Synlett. 2020 Feb;31(3):237-247. doi: 10.1055/s-0039-1691576. Epub 2020 Jan 16.
2
Kinetic and structural insight into the mechanism of BphD, a C-C bond hydrolase from the biphenyl degradation pathway.对来自联苯降解途径的碳-碳键水解酶BphD作用机制的动力学和结构洞察。
Biochemistry. 2006 Sep 19;45(37):11071-86. doi: 10.1021/bi0611098.