Kyono Wade, Coates Thomas D
Division of Pediatric Hematology-Oncology, University of Hawaii John A. Burns School of Medicine, Kapiolani Medical Center, Honolulu 96826, USA.
Pediatr Clin North Am. 2002 Oct;49(5):929-71, viii. doi: 10.1016/s0031-3955(02)00030-5.
This review discusses disorders of altered neutrophil number and function and provide a basic framework for patient evaluation and management. The sections begin with neutropenia, neutrophilia and neutrophil dysfunction with a general screening approach to differentiate common, more benign syndromes from rare, often more serious disorders. Also included is a detailed discussion of some specific primary neutrophil syndromes at the end of each section. Focus is placed on specific disorders that are clinically common or particularly instructive.
本综述讨论了中性粒细胞数量和功能改变的疾病,并为患者评估和管理提供了一个基本框架。各章节首先介绍中性粒细胞减少症、中性粒细胞增多症和中性粒细胞功能障碍,并采用一般筛查方法,以区分常见的、较良性的综合征与罕见的、通常更严重的疾病。各章节末尾还详细讨论了一些特定的原发性中性粒细胞综合征。重点关注临床上常见或具有特殊指导意义的特定疾病。