Hadley M N, Walters B C, Grabb P A, Oyesiku N M, Przybylski G J, Resnick D K, Ryken T C
Neurosurgery. 2002 Mar;50(3 Suppl):S63-72. doi: 10.1097/00006123-200203001-00013.
There is insufficient evidence to support treatment standards.
There is insufficient evidence to support treatment guidelines.
Treatment with methylprednisolone for either 24 or 48 hours is recommended as an option in the treatment of patients with acute spinal cord injuries that should be undertaken only with the knowledge that the evidence suggesting harmful side effects is more consistent than any suggestion of clinical benefit. GM-1 GANGLIOSIDE:
There is insufficient evidence to support treatment standards.
There is insufficient evidence to support treatment guidelines.
Treatment of patients with acute spinal cord injuries with GM-1 ganglioside is recommended as an option without demonstrated clinical benefit.
支持治疗标准的证据不足。
支持治疗指南的证据不足。
对于急性脊髓损伤患者,建议使用甲泼尼龙治疗24或48小时,此选项仅在知晓提示有害副作用的证据比任何临床获益提示更一致的情况下采用。GM-1神经节苷脂:
支持治疗标准的证据不足。
支持治疗指南的证据不足。
建议使用GM-1神经节苷脂治疗急性脊髓损伤患者,但该治疗未显示出临床获益。