Pankov A K, Mindlin S S, Verkhovtseva A I
Vopr Onkol. 1975;21(5):99-104.
An efficacy of the method of hormonal therapy--endolumbar hydrocortisone injection in patients with advanced breast cancer has been studied. A remission was gained in 28 of 41 patients. The method proved to be mostly effective in metastases in bones. Changes in the level of estrogens, 17-KS and 17-OCS excretion with the urine during the treatment indicate an endocrinous mechanism of this therapeutic effect. An efficacy of the method in extensive dissemination of the process, its relative simplicity and availability along with the absence of serious complications enabled the authors to hope that the suggested method may be widely used in practice.
对激素疗法——腰椎内注射氢化可的松治疗晚期乳腺癌患者的疗效进行了研究。41例患者中有28例获得缓解。该方法被证明对骨转移最为有效。治疗期间尿液中雌激素、17-酮类固醇和17-生氧皮质类固醇排泄水平的变化表明了这种治疗效果的内分泌机制。该方法在疾病广泛播散时的疗效、相对简单性和可行性以及无严重并发症，使作者们希望所建议的方法能在实践中得到广泛应用。
