鞘内注射芬太尼对硬膜外麻醉下剖宫产术中呕吐的抑制作用
[Inhibiting effect of intrathecal fentanyl on intraoperative vomiting during cesarean delivery under epidural anesthesia].
作者信息
Ouyang Ming-Wen, Gu Miao-Ning, Lin Chun-Shui
机构信息
Department of Anesthesia, Nanfang Hospital, First Military Medical University, Guangzhou 510515, China.
出版信息
Di Yi Jun Yi Da Xue Xue Bao. 2002 Nov;22(11):1037-8.
OBJECTIVE
To observe the inhibiting effect of intrathecal (IT) fentanyl on nausea and vomiting during cesarean delivery under epidural anesthesia.
METHODS
Thirty healthy parturients (ASA grade I to II) were randomly assigned in equal numbers into control and fentanyl groups (n=15 each, patients in the latter group treated with IT fentanyl at the dose of 20 microgram/3ml). The incidence of nausea and vomiting during the elective cesarean delivery under epidural anesthesia between the 2 groups were compared and the neonates' Apgar scores assessed after the delivery.
RESULTS
Intraoperative nausea and vomiting/retching were reduced in the IT fentanyl group as compared with the control group (6.7 % vs 33.3 % and 0 vs 26.7 %, P>0.05 and P<0.05 respectively). The neonates' Apgar scores were not significantly different between the 2 groups (P>0.05).
CONCLUSION
IT fentanyl can decrease intraoperative vomiting during cesarean delivery performed under epidural anesthesia.
目的
观察鞘内注射芬太尼对硬膜外麻醉剖宫产术中恶心呕吐的抑制作用。
方法
30例健康产妇（ASA分级Ⅰ～Ⅱ级）随机等分为对照组和芬太尼组（每组15例，芬太尼组患者鞘内注射20微克/3毫升芬太尼）。比较两组在硬膜外麻醉下行择期剖宫产术中恶心呕吐的发生率，并在产后评估新生儿阿氏评分。
结果
与对照组相比，鞘内注射芬太尼组术中恶心呕吐/干呕减少（分别为6.7%对33.3%和0对26.7%，P>0.05和P<0.05）。两组新生儿阿氏评分差异无统计学意义（P>0.05）。
结论
鞘内注射芬太尼可减少硬膜外麻醉剖宫产术中的术中呕吐。
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