Liu J L Y, Maniadakis N, Gray A, Rayner M
Health Economics Research Centre, Institute of Health Sciences, University of Oxford, Oxford, UK.
Heart. 2002 Dec;88(6):597-603. doi: 10.1136/heart.88.6.597.
To estimate the economic burden of coronary heart disease in the UK using both direct and indirect costs.
A prevalence based approach was used to assess coronary heart disease related costs from the societal perspective.
All UK residents in 1999 with coronary heart disease (ICD 9 codes 410-414 and ICD10 codes I20-I25).
Direct health care costs were estimated from spending on prevention, accident and emergency care, hospital care, rehabilitation, and drug treatment. Direct non-health service costs were estimated from data on informal care. "Friction period" adjusted productivity costs were estimated using the human capital approach from lost earnings attributable to coronary heart disease related mortality and morbidity. The friction period is the period of employees' absence from work before the employer replaces them with other workers. Failure to adjust for this factor would overstate production loss.
Coronary heart disease cost pound 1.73 billion to the UK health care system in 1999: pound 2.42 billion in informal care and pound 2.91 billion in friction period adjusted productivity loss; 24.1% of production losses were attributable to mortality and 75.9% to morbidity. The total annual cost of all coronary heart disease related burdens was pound 7.06 billion, the highest of all diseases in the UK for which comparable analyses have been done.
Coronary heart disease is a leading public health problem in the UK in terms of the economic burden from disease. Cost estimates would be substantially understated if informal care/productivity costs were excluded.
运用直接成本和间接成本评估英国冠心病的经济负担。
采用基于患病率的方法从社会角度评估与冠心病相关的成本。
1999年所有患有冠心病的英国居民(国际疾病分类第九版编码410 - 414以及国际疾病分类第十版编码I20 - I25)。
直接医疗成本通过预防、急诊护理、住院护理、康复及药物治疗方面的支出进行估算。直接非医疗服务成本根据非正式护理数据估算。“摩擦期”调整后的生产力成本采用人力资本法,根据冠心病相关死亡率和发病率导致的收入损失进行估算。摩擦期是指雇主用其他工人替代缺勤员工之前员工的缺勤时间。未对该因素进行调整会高估生产损失。
1999年冠心病给英国医疗系统造成了17.3亿英镑的成本:非正式护理方面为24.2亿英镑,“摩擦期”调整后的生产力损失为29.1亿英镑;生产损失的24.1%归因于死亡率,75.9%归因于发病率。所有与冠心病相关负担的年度总成本为70.6亿英镑,在英国所有已进行类似分析的疾病中位列最高。
就疾病造成的经济负担而言,冠心病是英国主要的公共卫生问题。若排除非正式护理/生产力成本,成本估算将被大幅低估。