Malta Loretta S, Blanchard Edward B, Taylor Ann E, Hickling Edward J, Freidenberg Brian M
Center for Stress and Anxiety Disorders, University of Albany, State University of New York, 1535 Western Ave., Albany, New York 12203, USA.
J Nerv Ment Dis. 2002 Nov;190(11):767-74. doi: 10.1097/00005053-200211000-00007.
This study examined the impact of a co-occurring personality disorder on the development and remission of posttraumatic stress disorder (PTSD) in 158 motor vehicle accident (MVA) survivors followed prospectively for 1 year. Participants were assessed 1 to 4 months after trauma and at 6-month and 1-year follow-up evaluations during 1991 through 1993. These archival data were analyzed in the present study. The prevalence of at least one personality disorder was 13.3%, with the majority (52.4%) presenting with obsessive-compulsive personality disorder. Persons with a personality disorder were significantly more likely to be diagnosed with PTSD at 1-year follow-up evaluation. For persons diagnosed with PTSD at the initial assessment, those with a personality disorder were significantly less likely to remit by 1 year. The presence of a preexisting personality disorder may increase the risk of chronic PTSD and impede remission.
本研究调查了158名机动车事故（MVA）幸存者中同时存在的人格障碍对创伤后应激障碍（PTSD）发生及缓解的影响，对这些幸存者进行了为期1年的前瞻性随访。在1991年至1993年期间，于创伤后1至4个月以及6个月和1年的随访评估时对参与者进行了评估。本研究对这些存档数据进行了分析。至少有一种人格障碍的患病率为13.3%，其中大多数（52.4%）表现为强迫型人格障碍。患有人格障碍的人在1年随访评估时被诊断为PTSD的可能性显著更高。对于在初始评估时被诊断为PTSD的人，患有人格障碍的人在1年内缓解的可能性显著更低。预先存在的人格障碍可能会增加慢性PTSD的风险并阻碍缓解。
