结构与毒蕈碱活性的关系III. 一些与2-甲基-4-三甲基铵甲基-1,3-二氧戊环碘化物相关的翁盐化合物的合成及胆碱能活性
Relation between structure and muscarinic activity III. Synthesis and cholinergic activity of some-onium compounds related to 2-methyl-4-trimethylammoniomethyl-1,3-dioxolane iodide.
作者信息
Elferink J G, Salemink C A
出版信息
Arzneimittelforschung. 1975;25(12):1858-60.
PMID:1243653
Abstract
The synthesis of the sulfonium, phosphonium and arsonium analogs of the dioxolane of Fourneau is described. The muscarinic activities of these compounds were compared with regard to the role of cationic head in the interaction with the muscarinic receptor.
摘要
描述了福尔诺二氧戊环的锍、鏻和胂类似物的合成。就阳离子头部在与毒蕈碱受体相互作用中的作用而言，比较了这些化合物的毒蕈碱活性。
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