[On the crystallisation of amphetaminil base into its hydrochloride salt (author's transl)].

In an aqueous medium in the presence of hydrochloric acid, amphetaminil (AN 1¿R) directly crystallises into the needle forming hydrochloride. The hydrochloride and base of the substance AN 1 have the same degree of insolubility in water. Such a reaction is relatively seldom observed in organic substances. Correspondingly, there is no similarity between the physical and chemical reactions of AN 1 and other well-known substances. In order to attain suitable judgement on the pharmaceutical/dynamic effect of AN 1, the clinical results known to date should not be disregarded.