Le Flohic A M, Silinghia D, Jacquemin J L, Jacquemin P
Bull Soc Pathol Exot Filiales. 1975 May-Jun;68(3):294-7.
Part of an inquiry which took place in R. C. A. from january 1972 to january 1975, we are able to give results concerning the prevalence of haemoglobin S in three new prospected regions and the value of sickling test. Cellogel electrophoresis sorted 20 0/0 of haemoglobin S bearers (AS or SS) od of 527 school children. On the same lot, sickling test by field practice, revealed only 7 0/0 and on the whole lot of examined individuals (684) only 8 0/0. This confirms that sickling test, when alone, is not reliable enough to appreciate the prevalence of haemoglobin S.
作为1972年1月至1975年在皇家癌症医院进行的一项调查的一部分,我们能够给出有关三个新勘探地区血红蛋白S的患病率以及镰变试验价值的结果。Cellogel电泳在527名学童中筛选出20%的血红蛋白S携带者(AS或SS)。在同一批样本中,现场实践的镰变试验仅检测出7%,而在所有检测个体(684名)中仅检测出8%。这证实了单独进行镰变试验时,其可靠性不足以评估血红蛋白S的患病率。