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氧化亚氮镇静下早产儿腹股沟疝修补术的脊髓麻醉:侧卧位或坐位腰椎穿刺的比较

Spinal anaesthesia for inguinal herniotomy in preterm infants sedated with nitrous oxide: a comparison of lumbar puncture in the lateral or sitting position.

作者信息

Vilà R, Lloret J, Munar F, Vinzo J

机构信息

Department of Anaesthesiology, Vall d'Hebron University Hospital, Barcelona, Spain.

出版信息

Anaesthesia. 2002 Dec;57(12):1164-7. doi: 10.1046/j.1365-2044.2002.02866.x.

DOI:10.1046/j.1365-2044.2002.02866.x
PMID:12437706
Abstract

This study compares spinal anaesthesia for inguinal herniotomy in preterm infants in the lateral or sitting position. Thirty patients were randomly divided into two equal groups. One hour before spinal anaesthesia, a eutetic mixture of local anaesthetic cream was applied to the lower lumbar spine. Sedation with nitrous oxide 50% in oxygen was given to all patients before and during induction of spinal anaesthesia, and throughout surgery. Lumbar punctures were performed at the L4-5 interspace using a 2.5 cm 22 G needle. Isobaric bupivacaine 0.5% with epinephrine 1 : 200 000 at a bupivacaine dose of 1 mg.kg-1 was injected in the lateral or sitting position. Measurements included heart rate, blood pressure, oxygen saturation, maximum sensory block height and duration of motor block and analgesia. There were no statistically significant differences between the groups in any measured parameters. Median [range] maximum block height was T5[T4-T7] in the lateral group and T5[T4-T5] in the sitting group. The median [range] duration of motor blockade was 67 [50-85] min in the lateral group and 63 [50-80] min in the sitting group. Our results indicate that in preterm infants sedated with nitrous oxide, spinal anaesthesia for inguinal herniotomy performed with isobaric bupivacaine 0.5% at a dose 1.0 mg.kg-1 in the lateral or sitting position is equally effective and is associated with minimal side effects.

摘要

本研究比较了早产儿腹股沟疝修补术采用侧卧位或坐位脊髓麻醉的效果。30例患者被随机分为两组,每组15例。脊髓麻醉前1小时,在下腰椎涂抹复方局部麻醉乳膏。在脊髓麻醉诱导前、诱导期间以及整个手术过程中,所有患者均吸入含50%氧化亚氮的氧气进行镇静。使用2.5 cm 22G穿刺针在L4 - 5椎间隙进行腰椎穿刺。于侧卧位或坐位注射0.5%等比重布比卡因与1:200 000肾上腺素混合液,布比卡因剂量为1mg·kg-1。监测指标包括心率、血压、血氧饱和度、最大感觉阻滞平面以及运动阻滞和镇痛持续时间。两组间任何测量参数均无统计学显著差异。侧卧位组最大阻滞平面中位数[范围]为T5[T4 - T7],坐位组为T5[T4 - T5]。侧卧位组运动阻滞持续时间中位数[范围]为67[50 - 85]分钟,坐位组为63[50 - 80]分钟。我们的结果表明,对于吸入氧化亚氮镇静的早产儿,采用0.5%等比重布比卡因、剂量1.0mg·kg-1于侧卧位或坐位进行腹股沟疝修补术的脊髓麻醉效果相同,且副作用最小。

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