Department of Anaesthesia, University of Port Harcourt Teaching Hospital, Port Harcourt, Nigeria.
Int J Obstet Anesth. 2013 Apr;22(2):124-8. doi: 10.1016/j.ijoa.2012.12.005. Epub 2013 Feb 27.
BACKGROUND: Hypotension during spinal anaesthesia occurs commonly in parturients. By influencing spread of local anaesthetic, maternal position may affect the speed of onset of sensory block and thus the haemodynamic effects. The aim of this study was to determine whether inducing spinal anaesthesia for caesarean section using plain bupivacaine in the lateral position would result in less hypotension compared with the sitting position. METHODS: One hundred American Society of Anesthesiologists physical status I and II patients undergoing elective caesarean section were randomised to receive spinal anaesthesia in the lateral position (Group L) or the sitting position (Group S). Using the L3-4 interspace, patients received intrathecal plain bupivacaine, 10mg or 12 mg according to their height, after which they were placed immediately in the supine position with left uterine displacement. Maternal blood pressure was measured every minute for 10 min, every three min for 20 min and 5-minutely thereafter. Hypotension was defined as a fall in systolic blood pressure >20% or a value <90 mmHg. RESULTS: There was no difference in the lowest recorded systolic blood pressure in Group L (99.2±8.9 mmHg) compared with Group S (95.4±12.3 mmHg, P=0.081). However, the lowest recorded mean arterial pressure was greater in Group L (72.9±11.2 mmHg) than in Group S (68.2±9.6 mmHg; P=0.025). The incidence of hypotension was lower in Group L (17/50, 34%) than in Group S (28/50, 56%; P=0.027). Onset of hypotension was similar between groups. CONCLUSION: Hypotension occurred less frequently when spinal anaesthesia for caesarean using plain bupivacaine was induced with patients in the lateral compared with the sitting position. Values for the lowest recorded mean arterial pressure were greater but values for the lowest recorded systolic blood pressure were similar for patients in the lateral position group.
背景:椎管内麻醉期间产妇常发生低血压。由于局麻药扩散的影响,产妇的体位可能会影响感觉阻滞的起始速度,从而影响血液动力学效应。本研究旨在确定在侧卧位下使用布比卡因行剖宫产术诱导椎管内麻醉是否会导致低血压的发生率低于坐位。
方法:100 例 ASA Ⅰ级和Ⅱ级的择期剖宫产患者随机分为侧卧位组(L 组)或坐位组(S 组)。使用 L3-4 间隙,根据身高给予患者 10mg 或 12mg 蛛网膜下腔注射布比卡因,然后立即在左侧子宫移位的仰卧位。在 10min 内每分钟测量一次产妇血压,在 20min 内每 3min 测量一次,此后每 5min 测量一次。低血压定义为收缩压下降>20%或<90mmHg。
结果:L 组(99.2±8.9mmHg)与 S 组(95.4±12.3mmHg,P=0.081)记录到的最低收缩压无差异。然而,L 组(72.9±11.2mmHg)记录到的最低平均动脉压大于 S 组(68.2±9.6mmHg;P=0.025)。L 组(17/50,34%)低血压的发生率低于 S 组(28/50,56%;P=0.027)。两组低血压的发生时间相似。
结论:与坐位相比,在侧卧位下使用布比卡因行剖宫产术诱导椎管内麻醉时,低血压的发生率较低。虽然侧卧位组的最低记录平均动脉压较高,但最低记录收缩压值相似。
Acta Anaesthesiol Scand. 2002-4
Anaesthesia. 2007-5