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残留前庭神经鞘瘤的治疗。

Treatment of residual vestibular schwannoma.

作者信息

Sanna Mario, Falcioni Maurizio, Taibah Abdelkader, De Donato Guiseppe, Russo Alessandra, Piccirillo Enrico

机构信息

Gruppo Otologico, Piacenzo-Roma, Italy.

出版信息

Otol Neurotol. 2002 Nov;23(6):980-7. doi: 10.1097/00129492-200211000-00028.

Abstract

OBJECTIVE

To evaluate the results of the surgical removal of residual vestibular schwannomas and compare them with results obtained from the first operation.

STUDY DESIGN

Retrospective case review.

SETTING

Tertiary otologic and skull base referral center. PATIENTS Twenty-three patients with residual vestibular schwannoma from a total of 637 patients who underwent surgery during the same time (April 1987 to April 2001). Only 1 patient had previously been treated in the same center. All but 1 patient had previously undergone at least 1 retrosigmoid approach. The majority of patients experienced an extensive list of complications and additional treatments after the first operation. Only 2 patients experienced some measurable hearing preoperatively. Previous hospitalization averaged 34.9 days, with a minimum of 5 and a maximum of 150 days.

INTERVENTIONS

16 patients were treated through an enlarged translabyrinthine approach and 7 through a modified transcochlear approach.

MAIN OUTCOME MEASURES

Total tumor removal, postoperative complications, hospital stay.

RESULTS

All but 2 patients underwent a total removal. Complications recorded were 1 temporary hemiparesis and aphasia, 1 subcutaneous abdominal hematoma, and 2 transitory VIth cranial nerve palsies. No additional treatment was required. The postoperative hospital stays ranged from 3 to 22 days, with a mean of 6.9.

CONCLUSIONS

Patients with vestibular schwannoma should be treated by an experienced team in a referral center to reduce postoperative morbidity and decrease the need to resort to only partial removal. Planned subtotal removal should be reserved for a few selected cases. The retrosigmoid approach is considered to have the highest risk that tumor remnants will unintentionally be left. In surgery of a residual vestibular schwannoma that has previously been treated through the retrosigmoid approach, the translabyrinthine approach offers some advantages with respect to performing another retrosigmoid procedure. In the presence of long-lasting facial palsy, the modified transcochlear approach represents the safest and most viable option available.

摘要

目的

评估手术切除残余前庭神经鞘瘤的结果,并将其与首次手术的结果进行比较。

研究设计

回顾性病例分析。

研究地点

三级耳科及颅底转诊中心。

患者

在同一时期(1987年4月至2001年4月)接受手术的637例患者中,有23例存在残余前庭神经鞘瘤。只有1例患者曾在同一中心接受过治疗。除1例患者外,所有患者此前至少接受过1次乙状窦后入路手术。大多数患者在首次手术后经历了一系列广泛的并发症和额外治疗。术前仅有2例患者有可测量的听力。既往住院时间平均为34.9天,最短5天,最长150天。

干预措施

16例患者采用扩大经迷路入路治疗,7例采用改良经耳蜗入路治疗。

主要观察指标

肿瘤全切率、术后并发症、住院时间。

结果

除2例患者外,其余患者均实现肿瘤全切。记录的并发症包括1例暂时性偏瘫和失语、1例皮下腹部血肿以及2例暂时性Ⅵ脑神经麻痹。无需额外治疗。术后住院时间为3至22天,平均为6.9天。

结论

前庭神经鞘瘤患者应由转诊中心经验丰富的团队进行治疗,以降低术后发病率,并减少仅行部分切除的必要性。计划性次全切除应仅保留给少数选定病例。乙状窦后入路被认为遗留肿瘤残余的风险最高。在先前通过乙状窦后入路治疗的残余前庭神经鞘瘤手术中,经迷路入路在再次进行乙状窦后手术方面具有一些优势。在存在长期面瘫的情况下,改良经耳蜗入路是最安全且最可行的选择。

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