Kobata Ritsuyo, Tsukahara Hirokazu, Nakai Akio, Tanizawa Akihiko, Ishimori Yoshiyuki, Kawamura Yasutaka, Ushijima Hiroshi, Mayumi Mitsufumi
Department of Pediatrics, Faculty of Medicine, Fukui Medical University, Fukui 910-1193, Japan.
J Comput Assist Tomogr. 2002 Sep-Oct;26(5):825-8. doi: 10.1097/00004728-200209000-00028.
The authors report serial brain MR findings from a 2-year-old girl with rotavirus encephalopathy. The lesion in the splenium of the corpus callosum showed restricted proton diffusion, suggesting local cytotoxic edema. Diffusion-weighted images demonstrated the lesion more conspicuously than other techniques, such as fluid-attenuated inversion-recovery and T1- and T2-weighted images. The findings were reversible on follow-up MRI obtained 4 days later. Diffusion-weighted MRI is a potentially useful method for detecting early changes of rotavirus encephalopathy, although the mechanism of the restricted diffusion is not clearly identified.
作者报告了一名患轮状病毒脑病的2岁女孩的系列脑部磁共振成像（MR）检查结果。胼胝体压部的病变显示质子扩散受限，提示局部细胞毒性水肿。扩散加权成像（DWI）比其他技术，如液体衰减反转恢复序列（FLAIR）、T1加权和T2加权成像，更能清晰地显示病变。在4天后的随访MRI检查中，这些表现是可逆的。尽管扩散受限的机制尚未明确，但扩散加权MRI是检测轮状病毒脑病早期变化的一种潜在有用方法。
