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无症状垂体瘤患者颞侧偏盲早期检测标准

Criteria for early detection of temporal hemianopia in asymptomatic pituitary tumor.

作者信息

Fujimoto N, Saeki N, Miyauchi O, Adachi-Usami E

机构信息

Department of Ophthalmology and Visual Science, Chiba University Graduate School of Medicine, Chiba, Japan.

出版信息

Eye (Lond). 2002 Nov;16(6):731-8. doi: 10.1038/sj.eye.6700165.

Abstract

PURPOSE

To determine new criteria for early detection of temporal hemianopia in patients with asymptomatic pituitary tumor.

METHODS

Fifteen patients without visual symptoms had pituitary tumor and subtle defects or normal visual fields by Goldmann perimetry. Twelve patients with visual symptoms had pituitary adenoma and visual field defects detected by Goldmann perimetry. All were examined by automated perimetry. The relationship between the tumor and the optic chiasm was graded by magnetic resonance imaging (MRI) on a scale of 0-4. Grade number increased with extent of compression. Temporal hemianopia observed by automated perimetry was estimated from normal data (52 normal fields). Vertical step was determined from the number of adjacent pairs along the midline; sensitivity was lower in the temporal field than in the nasal field. Temporal depression was calculated by the quadrant sum of sensitivity.

RESULTS

All patients with symptomatic pituitary adenoma had vertical step and temporal depression in the upper field. Nine of 15 patients without visual symptoms had vertical step or temporal depression. Of nine patients with temporal hemianopia, two of four patients had grade 1 compression, three of five had grade 2, and four of four had grade 3.

CONCLUSIONS

New criteria by automated perimetry could detect temporal hemianopia in patients with asymptomatic pituitary tumor.

摘要

目的

确定无症状垂体瘤患者早期检测颞侧偏盲的新标准。

方法

15例无视觉症状的患者患有垂体瘤,用戈德曼视野计检查显示有细微缺陷或视野正常。12例有视觉症状的患者患有垂体腺瘤,用戈德曼视野计检测到视野缺损。所有患者均接受自动视野计检查。通过磁共振成像(MRI)将肿瘤与视交叉的关系分为0 - 4级。分级数字随压迫程度增加。根据正常数据(52个正常视野)估算自动视野计观察到的颞侧偏盲情况。垂直阶梯由沿中线相邻对的数量确定;颞侧视野的敏感度低于鼻侧视野。颞侧凹陷通过敏感度的象限总和计算得出。

结果

所有有症状的垂体腺瘤患者在上半视野均有垂直阶梯和颞侧凹陷。15例无视觉症状的患者中有9例有垂直阶梯或颞侧凹陷。在9例颞侧偏盲患者中,4例中有2例为1级压迫,5例中有3例为2级,4例中有4例为3级。

结论

自动视野计的新标准可检测无症状垂体瘤患者的颞侧偏盲。

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