Duckett S, Cracco J, Graziani L, Scott T G, Solomon D, Kradin R
Acta Neurol Latinoam. 1975;21(1-4):184-93.
A 2 year old girl develops a fever, anorexia and a cough which last three weeks. Following this event, she presented with intention tremor and increasing difficulty with crawling. At the age of 3, a nerve biopsy was done which made the diagnosis of metachromatic leukodystrophy. EM examination of the nerve biopsy revealed large quantitites of abnormal structures in the cytoplasm of Schwann and phagocytic cells. Virus like spheroid bodies were present in a few axons and cytoplasm of Schwann cells.
一名2岁女童出现发热、食欲不振和咳嗽症状，持续了三周。此后，她出现了意向性震颤，爬行困难也日益加重。3岁时进行了神经活检，诊断为异染性脑白质营养不良。对神经活检标本进行电子显微镜检查发现，施万细胞和吞噬细胞的细胞质中有大量异常结构。少数轴突和施万细胞的细胞质中存在病毒样球状体。
