Lai I-Rue, Lee Yung-Chie, Lee Wei-Jei, Yuan Ray-Hwang
Department of Surgery, National Taiwan University Hospital, 7 Chung-Shan South Road, Taipei, Taiwan.
J Formos Med Assoc. 2002 Aug;101(8):547-51.
Laparoscopic antireflux surgery has recently been introduced as an alternative to laparotomy for the treatment of gastroesophageal reflux disease (GERD) at National Taiwan University Hospital. This study compared the results of traditional open and laparoscopic fundoplication for the treatment of GERD.
The surgical records and medical charts of 29 adult patients who were surgically treated for GERD between 1980 and 2001 were retrospectively reviewed. The clinical characteristics, indications for surgery, and surgical findings and procedures were analyzed.
Laparotomy and Nissen fundoplication were carried out on 20 of the patients between 1985 and 2000. Laparoscopic Nissen or Toupet fundoplication was performed on nine patients between 1997 and 2001. Patients in the laparoscopic group were younger than those in the laparotomy group (46.7 +/- 15.9 vs 58.3 +/- 18.5 yr). The incidence of associated prominent hiatal hernia was significantly higher in the laparotomy group (60 vs 33%). The mean operation time was 164.5 +/- 25.5 minutes in the laparotomy group and 182.2 +/- 52.2 minutes in the laparoscopy group (p = 0.6129). The mean hospital stay in the laparotomy group was significantly longer than that in the laparoscopy group (8.7 vs 3.4 days). Postoperative complications included three ventral hernias and one ileus in the laparotomy group. Results were good or excellent in 78.9% (15/19) of patients undergoing laparotomy (one patient was lost to follow-up 2 months later), and in 77.7% (7/9) of those undergoing laparoscopy. Symptomatic and endoscopic recurrence was recorded in two patients in the laparotomy group and one in the laparoscopy group.
Laparoscopic fundoplication is as effective as traditional laparotomy for treating GERD. More GERD patients in Taiwan, even the young and those without associated hiatal hernia, would rather undergo the less invasive and cosmetically better laparoscopic surgery than require medication throughout their lives.
在台湾大学医院,腹腔镜抗反流手术最近已被引入,作为治疗胃食管反流病(GERD)的开腹手术替代方案。本研究比较了传统开放手术和腹腔镜胃底折叠术治疗GERD的结果。
回顾性分析了1980年至2001年间接受GERD手术治疗的29例成年患者的手术记录和病历。分析了临床特征、手术指征以及手术发现和操作过程。
1985年至2000年间,20例患者接受了开腹手术及nissen胃底折叠术。1997年至2001年间,9例患者接受了腹腔镜nissen或Toupet胃底折叠术。腹腔镜组患者比开腹组患者年轻(46.7±15.9岁对58.3±18.5岁)。开腹组合并明显食管裂孔疝的发生率显著更高(60%对33%)。开腹组平均手术时间为164.5±25.5分钟,腹腔镜组为182.2±52.2分钟(p = 0.6129)。开腹组平均住院时间显著长于腹腔镜组(8.7天对3.4天)。开腹组术后并发症包括3例腹疝和1例肠梗阻。开腹手术患者中有78.9%(15/19)(1例患者术后2个月失访)、腹腔镜手术患者中有77.7%(7/9)的结果为良好或优秀。开腹组有2例患者、腹腔镜组有1例患者出现症状性和内镜下复发。
腹腔镜胃底折叠术治疗GERD与传统开腹手术同样有效。台湾更多的GERD患者,即使是年轻患者以及无相关食管裂孔疝的患者,也更愿意接受创伤较小且美观效果更好的腹腔镜手术,而非终身服药。