Merom Dafna, Ifrah Anneke, Cohen-Manheim Irit, Chinich Ayelet, Green Manfred S
Israel Center for Disease Control (ICDC), Gertner Institute for Epidemiology and Health Policy Research, Tel Hashomer, Israel.
Isr Med Assoc J. 2002 Sep;4(9):671-6.
Despite the controversy regarding the risks and benefits of hormone replacement therapy, studies in various countries report a two- to threefold increase in the use of HRT during the last decade.
To estimate the prevalence of HRT use among post-menopausal Jewish women in Israel and to determine the variables predicting current HRT use.
A cross-sectional telephone survey was conducted in 1998 on a random sample of Jewish women aged 45-74. Of 935 women who were located and eligible, 704 (75%) were interviewed by means of a structured questionnaire.
A total of 589 women (85%) were peri-menopausal or post-menopausal. Ninety-nine of them (16.8%) were currently using HRT and 78 (13.2%) were past users. Higher rates of current use were found among women who had undergone hysterectomy and/or oophorectomy (38%) than among all other women (13.5%). Among naturally menopausal women the highest rate of current use (25.6%) was found in those aged 55-59. A multiple logistic regression showed that the variables associated with current HRT use among naturally menopausal women were: having a regular gynecologist (odds ratio 3.6, 95% confidence interval 1.7-7.5), visiting a gynecologist during the past year (OR 2.9, 95% CI 1.4-6.0), experiencing symptoms of menopause (OR 2.0, 95% CI 1.01-3.8), having more than a high-school education (OR 1.9, 95% CI 1.04-3.6), and a lower body mass index (OR 0.91, 95% CI 0.85-0.99).
The factors associated with HRT use may be markers for other socioeconomic or psychological characteristics. The disparities noted between population subgroups may be indicative of differences in awareness or in the delivery of preventive healthcare services to women in Israel, and as such need to be addressed by the health system.
尽管激素替代疗法的风险和益处存在争议,但各国研究报告称,在过去十年中,激素替代疗法的使用增加了两到三倍。
评估以色列绝经后犹太妇女中激素替代疗法的使用 prevalence,并确定预测当前激素替代疗法使用情况的变量。
1998年对45-74岁犹太妇女的随机样本进行了横断面电话调查。在找到并符合条件的935名妇女中,704名(75%)通过结构化问卷进行了访谈。
共有589名妇女(85%)处于围绝经期或绝经后。其中99名(16.8%)目前正在使用激素替代疗法,78名(13.2%)曾使用过。接受过子宫切除术和/或卵巢切除术的妇女中当前使用率(38%)高于所有其他妇女(13.5%)。在自然绝经妇女中,55-59岁年龄组的当前使用率最高(25.6%)。多元逻辑回归显示,自然绝经妇女中与当前激素替代疗法使用相关的变量为:有固定的妇科医生(优势比3.6,95%置信区间1.7-7.5)、过去一年看过妇科医生(优势比2.9,95%置信区间1.4-6.0)、经历过更年期症状(优势比2.0,95%置信区间1.01-3.8)、受过高中以上教育(优势比1.9,95%置信区间1.04-3.6)以及较低的体重指数(优势比0.91,95%置信区间0.85-0.99)。
与激素替代疗法使用相关的因素可能是其他社会经济或心理特征的标志。人群亚组之间的差异可能表明以色列妇女在预防保健服务的认识或提供方面存在差异,因此卫生系统需要加以解决。