Studies on melanogenesis of tryptophan in Harding-Passey mouse melanoma.
作者信息
Costa C, Allegri G, De Antoni A
出版信息
Acta Vitaminol Enzymol. 1975;29(1-6):223-6.
PMID:1244096
Abstract
D,L-tryptophan[benzene ring-14C (U)] and D,L-tryptophan (methylene-14C) are incorporated significantly into melanin of Harding-Passey mouse melanoma. D,L-5-hydroxytryptophan (methylene-14C) and 5-hydroxytryptamine-3-14C (serotonin) gave an incorporation of radioactivity into melanin significantly lower than tryptophan. D,L-tyrosine-2-14C was incorporated into melanin as well as tryptophan. Therefore tryptophan must be considered an important precursor in the biogenesis of melanins too.
摘要
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