肥胖糖尿病患者和非糖尿病患者体重减轻的代谢效应。
Metabolic effects of weight reduction in obese diabetics and nondiabetics.
作者信息
Julius U, Schneider H, Leonhardt W, Hanefeld M, Gabsch H C
出版信息
Endokrinologie. 1976 Mar;67(1):96-102.
PMID:1244205
Abstract
A weight loss of about 10 kg was acheived by means of individual periods of total fasting, hypocaloric diets and physical activity in three groups of patients: maturity-onset diabetics, patients with pathological OGTT and overweight persons with normal OGTT. Adipocyte volume decreased in all groups, glucose tolerance improved. IRI curves showed a significant overall lowering and FFA concentrations during OGTT were dimished.
摘要
通过三组患者进行不同阶段的完全禁食、低热量饮食和体育活动，体重减轻了约10千克。这三组患者分别为成年型糖尿病患者、口服葡萄糖耐量试验（OGTT）异常的患者以及口服葡萄糖耐量试验正常的超重者。所有组的脂肪细胞体积均减小，葡萄糖耐量得到改善。胰岛素释放指数（IRI）曲线显示总体显著下降，口服葡萄糖耐量试验期间的游离脂肪酸（FFA）浓度降低。
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