• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

核酸成分及其类似物：一种从吡啶 -2(1H)-硫酮合成新型双吡啶和双杂环氮硫代糖苷的新颖有效方法。

Nucleic acid components and their analogues: a novel and efficient method for the synthesis of a new class of bipyridyl and biheterocyclic-nitrogen thioglycosides from pyridine-2(1H)-thiones.

作者信息

Elgemeie Galal H, El-Enany Mervat M, Ismail Mohamed M, Ahmed Eman K

机构信息

Chemistry Department, Faculty of Science, Helwan University, Ain-Helwan, Cairo, Egypt.

出版信息

Nucleosides Nucleotides Nucleic Acids. 2002 Jun-Jul;21(6-7):477-93. doi: 10.1081/NCN-120014820.

DOI:10.1081/NCN-120014820
PMID:12442965
Abstract

A novel synthesis of a new class of bipyridyl and biheterocyclic-nitrogen thioglycosides utilizing the reactions of heterocyclic substituted pyridine-2(1H)-thiones and alpha-bromoglucose or alpha-bromogalactose tetraacetate as starting components is described.

摘要

描述了一种新型双吡啶和双杂环氮硫代糖苷的合成方法，该方法利用杂环取代的吡啶 - 2(1H)-硫酮与α-溴葡萄糖或α-溴半乳糖四乙酸酯的反应作为起始原料。

相似文献

1
Nucleic acid components and their analogues: a novel and efficient method for the synthesis of a new class of bipyridyl and biheterocyclic-nitrogen thioglycosides from pyridine-2(1H)-thiones.核酸成分及其类似物：一种从吡啶 -2(1H)-硫酮合成新型双吡啶和双杂环氮硫代糖苷的新颖有效方法。
Nucleosides Nucleotides Nucleic Acids. 2002 Jun-Jul;21(6-7):477-93. doi: 10.1081/NCN-120014820.
2
A new class of biheterocyclic thioglycosides from pyridine-2-(1H)-thiones.一类新型的源自吡啶 - 2 -（1H）-硫酮的双杂环硫代糖苷。
Nucleosides Nucleotides Nucleic Acids. 2002 Nov-Dec;21(11-12):837-47. doi: 10.1081/NCN-120016511.
3
Nucleic acid components and their analogues: new synthesis of bicyclic thiopyrimidine nucleosides.
Nucleosides Nucleotides Nucleic Acids. 2000 Apr;19(4):723-33. doi: 10.1080/15257770008035020.
4
A direct route to 2-(beta-D-ribofuranosylthio)pyridine glycosides.通往2-(β-D-呋喃核糖硫基)吡啶糖苷的直接途径。
Nucleosides Nucleotides Nucleic Acids. 2002 Jun-Jul;21(6-7):411-6. doi: 10.1081/NCN-120014813.
5
One-pot synthesis of diverse 4-di(tri)fluoromethyl-3-cyanopyridine-2(1H)-thiones and their utilities in the cascade synthesis of annulated heterocycles.一锅法合成多种4-二（三）氟甲基-3-氰基吡啶-2（1H）-硫酮及其在稠合杂环的级联合成中的应用。
J Comb Chem. 2008 Mar-Apr;10(2):313-22. doi: 10.1021/cc7001793. Epub 2008 Feb 13.
6
Synthesis of unsymmetrical annulated 2,2'-bipyridine analogues with attached cycloalkene and piperidine rings via sequential Diels-Alder Reaction of 5,5'-bi-1,2,4-triazines.通过5,5'-双-1,2,4-三嗪的连续狄尔斯-阿尔德反应合成带有连接环烯烃和哌啶环的不对称稠合2,2'-联吡啶类似物。
Molecules. 2005 Dec 31;10(1):265-73. doi: 10.3390/10010265.
7
Porphyrins linked directly to the 5,5' positions of 2,2'-bipyridine: a new supramolecular building block and switch.直接连接到2,2'-联吡啶5,5'位的卟啉：一种新型超分子构建块与开关。
Inorg Chem. 2003 Mar 24;42(6):2075-83. doi: 10.1021/ic025985v.
8
Synthesis of a ruthenium(II) bipyridyl complex coordinated by a functionalized Schiff base ligand: characterization, spectroscopic and isothermal titration calorimetry measurements of M2+ binding and sensing (M2+=Ca2+, Mg2+).由功能化席夫碱配体配位的钌（II）联吡啶配合物的合成：M2 +结合与传感（M2 + = Ca2 +，Mg2 +）的表征、光谱和等温滴定量热法测量
Spectrochim Acta A Mol Biomol Spectrosc. 2009 Jul;73(1):29-34. doi: 10.1016/j.saa.2009.01.015. Epub 2009 Jan 29.
9
Direct inter- and intramolecular addition of amides to arylalkenes promoted by KOt-Bu/DMF.叔丁醇钾/二甲基甲酰胺促进的酰胺与芳基烯烃的直接分子间和分子内加成。
J Org Chem. 2014 Sep 19;79(18):8557-65. doi: 10.1021/jo501179t. Epub 2014 Sep 10.
10
"Turn-on" fluorescent sensor for the selective detection of zinc ion by a sterically-encumbered bipyridyl-based receptor.一种用于通过空间位阻联吡啶基受体选择性检测锌离子的“开启型”荧光传感器。
Chem Commun (Camb). 2007 Nov 28(44):4641-3. doi: 10.1039/b710740d. Epub 2007 Aug 31.

引用本文的文献

1
Anti-Covid-19 Drug Analogues: Synthesis of Novel Pyrimidine Thioglycosides as Antiviral Agents Against SARS-COV-2 and Avian Influenza H5N1 Viruses.抗新冠病毒药物类似物：新型嘧啶硫代糖苷作为抗SARS-CoV-2和禽流感H5N1病毒的抗病毒剂的合成
ACS Omega. 2021 Jun 24;6(26):16890-16904. doi: 10.1021/acsomega.1c01501. eCollection 2021 Jul 6.
2
Sofosbuvir Thio-analogues: Synthesis and Antiviral Evaluation of the First Novel Pyridine- and Pyrimidine-Based Thioglycoside Phosphoramidates.索磷布韦硫代类似物：首例新型吡啶基和嘧啶基硫代糖苷磷酰胺酯的合成及抗病毒评估
ACS Omega. 2020 Jun 9;5(24):14645-14655. doi: 10.1021/acsomega.0c01364. eCollection 2020 Jun 23.