Xu Ying, Glansdorff Nicolas
Microbiology, Free University of Brussels (VUB), JM Wiame Institute for Microbiology, 1 avenue Emile Gryzon, B-1070, Brussels, Belgium.
Comp Biochem Physiol A Mol Integr Physiol. 2002 Nov;133(3):677-88. doi: 10.1016/s1095-6433(02)00197-6.
In this paper we critically review the 'classical' model for the emergence of the three domains (Archaea, Bacteria, Eucarya), which presents hyperthermophilic procaryotes as the ancestors of all life on this planet. We come to the conclusion that our last common ancestor is likely to have been rather a non-hyperthermophilic protoeucaryote endowed with sn-1,2 glycerol ester lipids (as in modern Bacteria and Eucarya), from which Archaea emerged by streamlining under pressure for adapting to heat, a process which involved an important molecular innovation: the advent of sn-2,3 glycerol ether lipids. The nature of the primeval bacterial lines of descent is less clear; it would appear, nevertheless, that the first extreme- and hyperthermophilic Bacteria emerged by converging mechanisms; lateral gene transfer from Archaea may have played a role in this adaptation.
在本文中,我们批判性地审视了关于三个域(古菌、细菌、真核生物)起源的“经典”模型,该模型将嗜热原核生物视为地球上所有生命的祖先。我们得出的结论是,我们最后的共同祖先可能是一种非嗜热的原始真核生物,其具有sn-1,2甘油酯脂质(如现代细菌和真核生物中那样),古菌是在适应高温的压力下通过简化从这种生物中演化而来的,这一过程涉及一项重要的分子创新:sn-2,3甘油醚脂质的出现。原始细菌谱系的性质尚不清楚;然而,似乎第一批极端嗜热和嗜热细菌是通过趋同机制出现的;来自古菌的横向基因转移可能在这种适应过程中发挥了作用。