Lyon J L, Klauber M R, Gardner J W, Smart C R
N Engl J Med. 1976 Jan 15;294(3):129-33. doi: 10.1056/NEJM197601152940303.
Between 1950 and 1969 cancer mortality in white Utah residents was 22 per cent less than that in the entire United States population. The religion of 72 per cent of the State residents (Mormon) proscribes use of tobacco and alcohol. We therefore analyzed the 10,641 cases of cancer identified in Utah from 1966 to 1970 and compared the incidence found in Utah Mormons, in Utah non-Mormons, and in a national survey. Comparison of Utah Mormons with non-Mormons showed that Mormons had a lower incidence of all cancers associated with cigarette smoking (P less than 0.00001). Mormon females had a low incidence of cancer of the breast (P = 0.008), uterine cervix (P less than 0.00001), and ovary (P = 0.04); Mormon males had a lower incidence of stomach cancers (P = 0.003). These findings addevidence to the association between cigarette smoking and certain cancers, but leave unexplained the significant differences between Mormons and non-Mormons for incidence of cancer of the breast, cervix, prostate and nervous system.
1950年至1969年间，犹他州白人居民的癌症死亡率比美国总人口低22%。该州72%的居民（摩门教徒）信奉的宗教禁止吸烟和饮酒。因此，我们分析了1966年至1970年在犹他州确诊的10641例癌症病例，并比较了犹他州摩门教徒、犹他州非摩门教徒以及一项全国性调查中的癌症发病率。犹他州摩门教徒与非摩门教徒的比较显示，摩门教徒中与吸烟相关的所有癌症发病率较低（P<0.00001）。摩门教女性乳腺癌（P = 0.008）、子宫颈癌（P<0.00001）和卵巢癌（P = 0.04）的发病率较低；摩门教男性胃癌发病率较低（P = 0.003）。这些发现为吸烟与某些癌症之间的关联提供了证据，但摩门教徒与非摩门教徒在乳腺癌、子宫颈癌、前列腺癌和神经系统癌症发病率上的显著差异仍无法解释。
