Multari Domenico, Vascellari Marta, Mutinelli Franco
Istituto Zooprofilattico Sperimentale delle Venezie, Legnaro, Padova, Italy.
Vet Ophthalmol. 2002 Dec;5(4):273-6. doi: 10.1046/j.1463-5224.2002.00254.x.
A case of hemangiosarcoma of the third eyelid in a 15-year-old Domestic Short-haired cat is reported. A small red mass protruding from the anterior surface of the third eyelid in the left eye was present. Only mild bilateral conjunctivitis and nuclear sclerosis were revealed on initial ophthalmic examination. After anti-inflammatory treatment, surgery and cryotherapy were performed. On histopathologic examination the mass was located just beneath the conjunctival epithelium, suggesting that the conjunctiva was the tissue of origin. The tumor showed high cellularity and was composed of pleomorphic spindle and polygonal cells arranged in interlacing bundles and solid sheets. The presence of slit-like spaces between tumor cells containing erythrocytes demonstrated the vascular differentiation. Mitotic activity was moderate, but atypical mitoses were detected. The surgical area healed uneventfully and after 7 months there was no recurrence. To the authors' knowledge, this is the first report of conjunctival hemangiosarcoma of the third eyelid in a cat.
本文报告了一例15岁家养短毛猫第三眼睑血管肉瘤的病例。左眼第三眼睑前表面有一个小红肿块。初次眼科检查仅发现轻度双侧结膜炎和核硬化。抗炎治疗后,进行了手术和冷冻治疗。组织病理学检查显示肿块位于结膜上皮下方,提示结膜为起源组织。肿瘤细胞密度高,由多形性梭形细胞和多边形细胞组成,呈交错束状和实性片状排列。肿瘤细胞之间存在含有红细胞的裂隙样间隙,表明有血管分化。有丝分裂活性中等,但检测到非典型有丝分裂。手术区域愈合顺利,7个月后无复发。据作者所知,这是猫第三眼睑结膜血管肉瘤的首例报告。