Savolainen Peter, Zhang Ya-ping, Luo Jing, Lundeberg Joakim, Leitner Thomas
Department of Biotechnology, Royal Institute of Technology (KTH), 10691 Stockholm, Sweden.
Science. 2002 Nov 22;298(5598):1610-3. doi: 10.1126/science.1073906.
The origin of the domestic dog from wolves has been established, but the number of founding events, as well as where and when these occurred, is not known. To address these questions, we examined the mitochondrial DNA (mtDNA) sequence variation among 654 domestic dogs representing all major dog populations worldwide. Although our data indicate several maternal origins from wolf, >95% of all sequences belonged to three phylogenetic groups universally represented at similar frequencies, suggesting a common origin from a single gene pool for all dog populations. A larger genetic variation in East Asia than in other regions and the pattern of phylogeographic variation suggest an East Asian origin for the domestic dog, approximately 15,000 years ago.
家犬起源于狼这一点已得到证实，但最初的驯化事件数量以及这些事件发生的地点和时间尚不清楚。为了解决这些问题，我们检测了代表全球所有主要犬类种群的654只家犬的线粒体DNA（mtDNA）序列变异情况。尽管我们的数据表明家犬有多个母系起源于狼，但所有序列中超过95%属于三个系统发育组，这些组在全球普遍以相似的频率存在，这表明所有犬类种群都起源于一个共同的基因库。东亚地区的遗传变异比其他地区更大，系统发育地理变异模式表明家犬大约在15000年前起源于东亚。
